Differential effects of antihypertensive drug therapy on arterial compliance
نویسندگان
چکیده
منابع مشابه
Differential effects of antihypertensive drug therapy on arterial compliance.
Although vascular compliance, deltaV/deltaP, is abnormal in essential hypertension and can be improved by antihypertensive drug therapy, it is not clear whether drug-induced changes in compliance are attributable solely to lower achieved blood pressure (BP), and thus equally likely with different drugs possessing similar antihypertensive efficacy. Therefore, we used computerized arterial pulse ...
متن کاملAppraisal of antihypertensive drug therapy.
SUMMARY Four completed prospective studies of drug-treated and control hypertensives utilizing double blind ran-domized protocols are reviewed for the purpose of evaluating the evidence on which the present therapeutic crusade is based. Patients studied were predominantly male, observed for short period, had complications or died at young age, had high incidence of previous target organ vascula...
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Increased central arterial stiffness, involving accelerated vascular ageing of the aorta, is a powerful and independent risk factor for early mortality and provides prognostic information above and beyond traditional risk factors for cardiovascular disease (CVD). Central arterial stiffness is an important determinant of pulse pressure; therefore, any pathological increase may result in left ven...
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Several drugs used for standard antihypertensive therapy may also interact with the lipoprotein metabolism. The following has been observed after 1 to 12 months of treatment. Various thiazide-type diuretics may significantly increase the potentially atherogenic serum low-density-lipoprotein cholesterol (LDL-C) and/or very-LDL-C-fractions, while the antiatherogenic high-density-lipoprotein chole...
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DR. HERBERT CHASIS has long been known for his skepticism with respect to the treatment of hypertension. Indeed, it was the skepticism of Drs. Goldring, Chasis and Perera which served as an important stimulus in planning the Veterans Administration Cooperative Study. Dr. Chasis completely rejects the concept that the cardiovascular damage seen in hypertension is the consequence of the elevated ...
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ژورنال
عنوان ژورنال: American Journal of Hypertension
سال: 2000
ISSN: 0895-7061
DOI: 10.1016/s0895-7061(00)00349-6